Some really good points being made in this thread, but frankly we are talking about stuff we all know in retrospect. Had i been given the chance to save lifespan by skipping "infec...." er, the episode JDM referred to, I would have. I cannot have that hour of lifespan back
On the other hand, there is a lot to be said for slogging one's way though even the non-JMS-written episodes of the first season, so that one gets an appreciation for good writing when it becomes more focussed in the later seasons. Further, skipping season one means missing out on the truly gob-stopping moment of the entire five years of the show (not the best in terms of CGI, but the one moment when you jump out of your chair and go "WHAT THE F... WAS THAT?") I remember how excited my girlfriend amd I were at the conclusion of this ep because we finally knew we were not in Kansas any more. If you watch it later, after you have learned to recognize what was going on, you miss all the punch. And that would be a shame.
So, like others, I say somewhat reluctantly that it is best to watch the series from the start, and to endure what must be endured (in the sure hope that your faith will be rewarded). If you lack the patience for all the eps, watch the ones 2aMageing recommends or go to the Lurker's Guide and heck out the heavy arcs ones they recommend.
Ironically, though I have seen the series many times and each ep at will since it came out on DVD, I only just a couple of weeks ago realized that there was yet another connection between events in Season one's Crysalis and thre movie In the Beginning done three-plus years later. There always is something new to discover, because the series is that deep and that well-thought-out. Ten years later, and it still surprises me.
But I agree with Doctor Gonzo that if you start to lose faith that the show will interest you, have "In the Beginning" in your hip pocket as an elixer of life. That TV movie is quite disjointed as it tries to show every major charactor in the war that occurs ten years before the premier, but the payoff is so stupendous in terms of script, acting, and music that if you finish it dry-eyed you may need professional help. It DOES spoil some things, but bettter to watch things after spoilers than give up on the series.
Just don't stop short of Sleeping in Light.