First of all, it's an absolutely storming story. That is primarily what jms set out to do and he succeeded in spades.
Secondly, B5 has given me so much over the last nine years. Because of that station, I have gained;
Two good friends,
The inspiration to finish writing my book after ten years,
An introduction to fan fiction,
A greater understanding of life through jms' writing in the show,
Using the above, some comfort during a couple of low periods in my life in the last seven years,
An escape from the daily grind once a week, or when I watch the vids,
A whole new community of people as wacky as me, through conventions and the internet.
No other show has affected my life so completely before. I doubt there will be another.